Molecular Formula | C18H26N6OS |
Molar Mass | 374.5 |
Density | 1.33±0.1 g/cm3(Predicted) |
Boling Point | 599.6±60.0 °C(Predicted) |
Solubility | 10 mM in DMSO |
pKa | 14.56±0.10(Predicted) |
Storage Condition | -20℃ |
1mg | 5mg | 10mg | |
---|---|---|---|
1 mM | 2.67 ml | 13.351 ml | 26.702 ml |
5 mM | 0.534 ml | 2.67 ml | 5.34 ml |
10 mM | 0.267 ml | 1.335 ml | 2.67 ml |
5 mM | 0.053 ml | 0.267 ml | 0.534 ml |
biological activity | GV-58 are N-and P/Q-type calcium channel agonists, with EC50 values of 7.21 and 8.81uM respectively, and their inhibitory effect on CDK kinases is 20 times weaker, which is the optimized compound of (R)-roscovitine. |